Using MESOPURE®, Univercell-Biosolutions has developed processes yielding pure populations of mature iPS-derived human endothelial cells with the capacity to form vessel-like structures in vitro. These cells are an ideal in vitro model system for targeted vascular drug discovery.
CD 15+ cells after selection
ED-ONE® human endothelial cells| ED-ONE® Endothelial cells: product specifications | ||
| Cell Type | Endothelium | |
| Organism | Human | |
| Origin | Human iPS cell lines | |
| Endothelial biomarkers | CD31, CD34, VE cadherin, KDR | |
| Quantity | 24 or 96 well plates | |
| Shipped | Freshly or frozen | |
| Storage | Frozen | |
| Viability | Up to 2 weeks in culture | |
Advantages : maximization and preservation of the predictability
- Human cells
- Endothelium derived human iPS cell line
- Ready to use
- Highly homogeneous and pure
- Maturity level close to adult human endothelium cells
- Physiologic Sort out method
Applications:
- Cell proliferation
- Cell permeability
- Tubular formation
References: Publications
A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in post-myocardial infarcted non-human primates
Blin G*, Nury*, D, Stefanovic*, S, Neri, T, Guillevic, O, Brinon, B, Bellamy, V, Rücker-Martin, C, Barbry, P, Bel, A, Bruneval, P, Cowan, C, Pouly, J, Mitalipov, S, Gouadon, E, Binder,P, Hagège, A, Desnos, M, Renaud, JF, Menasché, M, Pucéat,M. *co-1st authors.. J Clin. Invest. 2010 120(4):1125-39